UNLV Prof. Parsun Guha’s Lab Research: Key to Managing Leaky Gut Could Lie in Common Compound We’re Already Eating
In a study published formally on May 28 in the journal Nature Communications, the team shares how phytic acid (or InsP6), a natural compound found in whole grains, beans, lentils, nuts, and seeds, plays an important role in maintaining the integrity of the intestinal barrier.
“Phytic acid is something many people already consume daily, especially in plant-rich diets,” said Sujan Chatterjee, a UNLV postdoctoral fellow and lead author on the study. “What’s exciting is that it’s beyond just a dietary component; it also functions as a biologically active molecule that supports gut health.”
Parson Guha emphasized that while more research is needed, this work opens the door to a potential new class of therapies that are safer, more natural, and focused on restoring the body’s own protective systems.
“The future of medicine may lie at the intersection of nutrition, metabolism, and epigenetics,” Guha says.



